Navigating Office Chit-Chat: To Respond or Not to Respond?

just wanna grab you for 2 secs
if I’m in the office and someone next to me is like
“Oh I’m so tired”
“Oh I don’t know what to do”
“I’m too warm”
blah blah blah blah am I meant to respond
is that a key for conversation
and am I a bitch if I don’t respond
see I’m normally work from home girly
been 4 years so I’m so not used to thenon-politics in the office
but I need to know